Rezaei N. Translational Autoimmunity. Vol 3. 2022

Textbook in PDF format

Translational Autoimmunity: Autoimmune Diseases in Different Clinical Settings addresses autoimmunity and associated conditions, such as aging, infectious diseases, cancer, neurodegeneration, psychological disorders, fertility, inflammatory vascular diseases, and interstitial lung diseases. The book addresses sufficiently basic questions on how the immune system is designed to distinguish self from no self and behave such that it's able to maintain self-tolerance, how does it work in infections, and how it elicits an auto-reactive state and develops self-antigens seen in autoimmune conditions. This is followed by an overview on the genetic and clinical aspects of the spectrum of autoimmune diseases which are broadly categorized into two types of organ specific autoimmune diseases and non-organ specific autoimmune diseases (also known as systemic autoimmune diseases).
Introduction on autoimmunity and associated conditions
Cross talks between autoimmunity and cancer
Autoimmunity regulation within the tumor microenvironment
Mechanisms of immune tolerance breakdown in inborn errors of immunity
Autoimmunity in combined immunodeficiency
Autoimmunity and autoimmune diseases in primary selective IgM deficiency
Autoimmunity and HIV infection
Autoimmune diseases and metabolic disorders: Molecular connections and potential therapeutic targets
Autoimmunity and infertility
Autoimmune disease of the cardiovascular system
Allergy and autoimmunity: Share of genetics and environment
Asthma and autoimmunity
Autoimmunity in interstitial lung disease
Role of autoimmunity in the pathogenesis of chronic obstructive pulmonary disease and pulmonary emphysema
Oxidative stress in oral autoimmune disorders
Autoimmunity and psychosis