| 1 - Introduction English.srt | 4.6 KB | ||
| 1 - Introduction.mp4 | 86 MB | ||
| 10 - Framework region English.srt | 1.6 KB | ||
| 10 - Framework region.mp4 | 8.8 MB | ||
| 11 - Binding of antigen to CDRs English.srt | 3.3 KB | ||
| 11 - Binding of antigen to CDRs.mp4 | 18.5 MB | ||
| 12 - Role of Hinge Region English.srt | 2.9 KB | ||
| 12 - Role of Hinge Region.mp4 | 21.6 MB | ||
| 13 - Summary Detailed structure of antibodies English.srt | 4 KB | ||
| 13 - Summary Detailed structure of antibodies.mp4 | 46.4 MB | ||
| 14 - Immunoglobulin G or IgG English.srt | 5 KB | ||
| 14 - Immunoglobulin G or IgG.mp4 | 47.2 MB | ||
| 15 - Immunoglobulin A or IgA English.srt | 6.2 KB | ||
| 15 - Immunoglobulin A or IgA.mp4 | 53 MB | ||
| 16 - Immunoglobulin M or IgM English.srt | 5.1 KB | ||
| 16 - Immunoglobulin M or IgM.mp4 | 30.6 MB | ||
| 17 - Immunoglobulin E or IgE English.srt | 5 KB | ||
| 17 - Immunoglobulin E or IgE.mp4 | 29.2 MB | ||
| 18 - Immunoglobulin D or IgD English.srt | 1.5 KB | ||
| 18 - Immunoglobulin D or IgD.mp4 | 6.7 MB | ||
| 19 - Summary Antibody classes and their biological activities English.srt | 7.3 KB | ||
| 19 - Summary Antibody classes and their biological activities.mp4 | 73.3 MB | ||
| 2 - Basic structure of immunoglobulins or antibodies English.srt | 5.4 KB | ||
| 2 - Basic structure of immunoglobulins or antibodies.mp4 | 48.2 MB | ||
| 20 - Introduction to complement system English.srt | 3 KB | ||
| 20 - Introduction to complement system.mp4 | 26.3 MB | ||
| 21 - Nomenclature of complement proteins English.srt | 2.3 KB | ||
| 21 - Nomenclature of complement proteins.mp4 | 10.9 MB | ||
| 22 - Classical pathway of complement activation English.srt | 5.7 KB | ||
| 22 - Classical pathway of complement activation.mp4 | 43.3 MB | ||
| 23 - Alternative pathway of complement activation English.srt | 4.9 KB | ||
| 23 - Alternative pathway of complement activation.mp4 | 20.1 MB | ||
| 24 - Lectin Pathway of complement activation English.srt | 2.4 KB | ||
| 24 - Lectin Pathway of complement activation.mp4 | 10.6 MB | ||
| 25 - Membrane Attack Complex MAC English.srt | 4.7 KB | ||
| 25 - Membrane Attack Complex MAC.mp4 | 21.6 MB | ||
| 26 - Summary Complement system English.srt | 4.1 KB | ||
| 26 - Summary Complement system.mp4 | 17.8 MB | ||
| 27 - Regulation of the complement system English.srt | 9.4 KB | ||
| 27 - Regulation of the complement system.mp4 | 56.5 MB | ||
| 28 - Other functions of complement proteins English.srt | 4.4 KB | ||
| 28 - Other functions of complement proteins.mp4 | 23.5 MB | ||
| 29 - Germline & somatic hypermutation Theory English.srt | 3.3 KB | ||
| 29 - Germline & somatic hypermutation Theory.mp4 | 19.8 MB | ||
| 3 - Functional components of Antibodies English.srt | 4.7 KB | ||
| 3 - Functional components of Antibodies.mp4 | 19.3 MB | ||
| 30 - Tonegawa’s Theory Immunoglobulin genes rearrange English.srt | 4.9 KB | ||
| 30 - Tonegawa’s Theory Immunoglobulin genes rearrange.mp4 | 24.4 MB | ||
| 31 - Organization of Ig genes English.srt | 5.9 KB | ||
| 31 - Organization of Ig genes.mp4 | 36.1 MB | ||
| 32 - Organization of gene segments encoding light chains English.srt | 3.3 KB | ||
| 32 - Organization of gene segments encoding light chains.mp4 | 23.9 MB | ||
| 33 - Organization of gene segments encoding heavy chains English.srt | 3.8 KB | ||
| 33 - Organization of gene segments encoding heavy chains.mp4 | 22.6 MB | ||
| 34 - VJ recombination in kappa light chain DNA English.srt | 3.7 KB | ||
| 34 - VJ recombination in kappa light chain DNA.mp4 | 20.7 MB | ||
| 35 - VJ recombination in ƛ light chain DNA English.srt | 3 KB | ||
| 36 - VDJ recombination in heavy chain DNA English.srt | 2.8 KB | ||
| 36 - VDJ recombination in heavy chain DNA.mp4 | 15.1 MB | ||
| 37 - Mechanism of variable region DNA rearrangements English.srt | 6.5 KB | ||
| 37 - Mechanism of variable region DNA rearrangements.mp4 | 50.1 MB | ||
| 38 - Combinatorial VJ and VDJ joining English.srt | 2.8 KB | ||
| 38 - Combinatorial VJ and VDJ joining.mp4 | 24.2 MB | ||
| 39 - Junctional Flexibility English.srt | 2.6 KB | ||
| 39 - Junctional Flexibility.mp4 | 17.2 MB | ||
| 4 - Summary Basic structure of antibodies English.srt | 1.6 KB | ||
| 4 - Summary Basic structure of antibodies.mp4 | 8.2 MB | ||
| 40 - Paddition English.srt | 5.2 KB | ||
| 40 - Paddition.mp4 | 29.7 MB | ||
| 41 - Naddition English.srt | 3.9 KB | ||
| 41 - Naddition.mp4 | 21 MB | ||
| 42 - Somatic Hypermutation English.srt | 7 KB | ||
| 42 - Somatic Hypermutation.mp4 | 54.6 MB | ||
| 43 - Class switching English.srt | 3.9 KB | ||
| 43 - Class switching.mp4 | 20.8 MB | ||
| 44 - Mechanism of class switching English.srt | 4.9 KB | ||
| 44 - Mechanism of class switching.mp4 | 27.9 MB | ||
| 45 - Factors that govern class switching English.srt | 3 KB | ||
| 45 - Factors that govern class switching.mp4 | 25.3 MB | ||
| 46 - Membrane bound immunoglobulins and BCRs English.srt | 5.6 KB | ||
| 46 - Membrane bound immunoglobulins and BCRs.mp4 | 48.9 MB | ||
| 47 - Expression of membrane bound or secreted Immunoglobulin English.srt | 4.9 KB | ||
| 47 - Expression of membrane bound or secreted Immunoglobulin.mp4 | 30.7 MB | ||
| 48 - Simultaneous expression of IgM and IgD on mature B cells English.srt | 2.5 KB | ||
| 48 - Simultaneous expression of IgM and IgD on mature B cells.mp4 | 15.1 MB | ||
| 49 - Regulatory sequences in DNA English.srt | 4 KB | ||
| 49 - Regulatory sequences in DNA.mp4 | 21.2 MB | ||
| 5 - Antibody sequencing to know different types of light and heavy chains of Abs English.srt | 3.1 KB | ||
| 5 - Antibody sequencing to know different types of light and heavy chains of Abs.mp4 | 16.8 MB | ||
| 50 - Allelic exclusion English.srt | 6.7 KB | ||
| 50 - Allelic exclusion.mp4 | 56.4 MB | ||
| 51 - Mechanism of allelic exclusion English.srt | 3.7 KB | ||
| 51 - Mechanism of allelic exclusion.mp4 | 13.9 MB | ||
| 52 - Isotypic determinants English.srt | 4 KB | ||
| 52 - Isotypic determinants.mp4 | 21.6 MB | ||
| 53 - Role of antiisotype antibodies in detection of viral diseases English.srt | 2.5 KB | ||
| 53 - Role of antiisotype antibodies in detection of viral diseases.mp4 | 21.5 MB | ||
| 54 - Allotypic determinants English.srt | 2.9 KB | ||
| 54 - Allotypic determinants.mp4 | 17.6 MB | ||
| 55 - Idiotypic determinants English.srt | 2.8 KB | ||
| 55 - Idiotypic determinants.mp4 | 15.1 MB | ||
| 56 - Types of antiID antibodies English.srt | 2 KB | ||
| 56 - Types of antiID antibodies.mp4 | 8.3 MB | ||
| 57 - Specific uses of antiID antibodies English.srt | 6.6 KB | ||
| 57 - Specific uses of antiID antibodies.mp4 | 29.6 MB | ||
| 58 - Polyclonal Antibodies English.srt | 5.2 KB | ||
| 58 - Polyclonal Antibodies.mp4 | 28.3 MB | ||
| 59 - Monoclonal Antibodies English.srt | 3.1 KB | ||
| 59 - Monoclonal Antibodies.mp4 | 13.5 MB | ||
| 6 - Types of light chains English.srt | 2.5 KB | ||
| 6 - Types of light chains.mp4 | 9.6 MB | ||
| 60 - Hybridoma Technology Production of Monoclonal Antibodies English.srt | 4.3 KB | ||
| 60 - Hybridoma Technology Production of Monoclonal Antibodies.mp4 | 18.5 MB | ||
| 61 - Selection of Hybridoma cells producing Monoclonal Antibodies English.srt | 6.5 KB | ||
| 61 - Selection of Hybridoma cells producing Monoclonal Antibodies.mp4 | 34.6 MB | ||
| 62 - Advantages of therapeutic monoclonal antibodies over conventional drugs English.srt | 4.2 KB | ||
| 62 - Advantages of therapeutic monoclonal antibodies over conventional drugs.mp4 | 16.1 MB | ||
| 63 - Chimeric Monoclonal Antibodies English.srt | 5.3 KB | ||
| 63 - Chimeric Monoclonal Antibodies.mp4 | 33.4 MB | ||
| 64 - Humanized Monoclonal Antibodies English.srt | 4.4 KB | ||
| 64 - Humanized Monoclonal Antibodies.mp4 | 22.4 MB | ||
| 65 - Fully Human Monoclonal Antibodies English.srt | 7.1 KB | ||
| 65 - Fully Human Monoclonal Antibodies.mp4 | 46.7 MB | ||
| 66 - Isolation of monoclonal antibodies directly from humans English.srt | 3.7 KB | ||
| 66 - Isolation of monoclonal antibodies directly from humans.mp4 | 24.7 MB | ||
| 67 - Immunogenicity of engineered monoclonal antibodies English.srt | 3.9 KB | ||
| 67 - Immunogenicity of engineered monoclonal antibodies.mp4 | 21.2 MB | ||
| 68 - Immunotoxins English.srt | 5.5 KB | ||
| 68 - Immunotoxins.mp4 | 27.1 MB | ||
| 69 - Recombinant Immunotoxins English.srt | 1.5 KB | ||
| 69 - Recombinant Immunotoxins.mp4 | 5.5 MB | ||
| 7 - Types of heavy chains English.srt | 2.9 KB | ||
| 7 - Types of heavy chains.mp4 | 12.3 MB | ||
| 70 - Humanised and Fully Human Immunotoxins English.srt | 2 KB | ||
| 70 - Humanised and Fully Human Immunotoxins.mp4 | 8.2 MB | ||
| 71 - Bispecific Antibodies or Heteroconjugates English.srt | 3 KB | ||
| 71 - Bispecific Antibodies or Heteroconjugates.mp4 | 11.4 MB | ||
| 72 - Abzymes English.srt | 6.2 KB | ||
| 72 - Abzymes.mp4 | 23.2 MB | ||
| 73 - Structural proteins of SARSCoV2 English.srt | 3.7 KB | ||
| 73 - Structural proteins of SARSCoV2.mp4 | 40 MB | ||
| 74 - What is Plasma Therapy or Passive Immunization English.srt | 7.2 KB | ||
| 74 - What is Plasma Therapy or Passive Immunization.mp4 | 42.6 MB | ||
| 75 - How is plasma therapy done English.srt | 3.6 KB | ||
| 75 - How is plasma therapy done.mp4 | 13.6 MB | ||
| 76 - Limitations of Plasma Therapy English.srt | 2.8 KB | ||
| 76 - Limitations of Plasma Therapy.mp4 | 11.6 MB | ||
| 77 - Monoclonal antibodies and COVID19 English.srt | 3.2 KB | ||
| 77 - Monoclonal antibodies and COVID19.mp4 | 12.6 MB | ||
| 78 - Isolation of monoclonal antibodies from COVID19 recovered patients English.srt | 4.7 KB | ||
| 78 - Isolation of monoclonal antibodies from COVID19 recovered patients.mp4 | 25.8 MB | ||
| 79 - How plasma therapy & monoclonal antibody therapy are different from vaccination English.srt | 3.7 KB | ||
| 79 - How plasma therapy & monoclonal antibody therapy are different from vaccination.mp4 | 14.8 MB | ||
| 8 - Immunoglobulin Domains English.srt | 4.6 KB | ||
| 8 - Immunoglobulin Domains.mp4 | 27.6 MB | ||
| 80 - Whats next.html | 2.5 KB | ||
| 9 - Complementarity determining regions CDRs English.srt | 4.4 KB | ||
| 9 - Complementarity determining regions CDRs.mp4 | 42.9 MB | ||
| Bonus Resources.txt | 409.6 B | ||
| Get Bonus Downloads Here.url | 204.8 B | ||
| ▲ 160 total files | |||
Biotechnology: Antibodies & Their Role In Therapeutics
https://TutGator.com
Last updated 9/2022
MP4 | Video: h264, 1280x720 | Audio: AAC, 44.1 KHz
Language: English | Size: 2.02 GB | Duration: 5h 33m
Learn about Antibodies: Their Structure, Types, Functions and Role in Therapeutics & Diagnostics | Immunology | Biology
What you'll learn
1. Structure of antibodies
2. Types of light and heavy chains of antibodies
3. Complementarity Determining Regions (CDRs) & how they bind to antigen
4. Immunoglobulin domains
5. Framework region
6. Classes of antibodies: IgG, IgM, IgA, IgE, IgD & their biological activities
7. What is opsonization, ADCC and complement system
8. Pathways of complement activation
9. Regulation of complement system
10. Organization and expression of immunoglobulin genes
11. Mechanism of VJ and VDJ recombination
12. Generation of antibody diversity
13. Somatic Hypermutation
14. Class switching mechanism & factors governing it
15. Expression of membrane bound & secreted form of immunoglobulins
16. B cell receptors (BCRs)
17. Simultaneous expression of IgM and IgD on B cells
18. Regulation of Ig gene transcription
19. Differences between polyclonal and monoclonal antibodies
20. Hybridoma Technology
21. Therapeutic monoclonal antibodies
22. Antibody engineering: Chimeric monoclonal antibodies
23. Humanized monoclonal antibodies
24. Fully human monoclonal antibodies
25. Immunogenicity of engineered monoclonal antibodies
26. Immunotoxins
27. Bispecific antibodies
28. Abzymes
29. Convalescent plasma therapy
30. How is plasma therapy being used for the treatment of COVID-19 disease
Requirements
Knowledge of basic biology
Motivation to learn
Description
Immune system is the body’s own army that fights against the invading pathogens and toxins. You can compare it to a nation’s defense forces. The army, the air force and the navy all work for the nation's defense. Similarly, the immune system works for the body’s defense. Everywhere around us, there are dangerous bacteria, viruses, parasites and toxins that can attack and harm our body. But our immune system defends us from these pathogens.Antibodies, also known as immunoglobulins, are one of the crucial warriors produced by our immune system to fight off these nasty invading pathogens. In absence of antibodies, these pathogens can attack our nerve cells, kidney cells, heart cells and other vital parts of the body.Once attacked by these nasty pathogens, the cells stop functioning, which in turn, may lead to serious illness. But when antibodies come into action, everything changes. They bind to the invading pathogens and prevent them from attacking our body cells.So what do these antibodies look like, what is their structure and how do they fight off such dangerous pathogens? If you are also curious about these concepts and want to learn the science behind it, then you have come to the right place.This course is an invaluable resource for medical students, doctors and students of disciplines like biotechnology, biology, immunology, genetics, molecular biology, cell biology and bioinformatics. In the course, the most challenging concepts are presented in a simple and palatable format using animations and graphics.This course will cover different types of antibodies circulating in the bloodstream & tissue fluids and their respective functions. Additionally this course will also cover the genetic mechanisms which allow our immune system to generate such a diverse pool of antibodies because of which our body is able to recognize and respond to a variety of antigens.Further in this course, the class switching mechanism, expression of membrane bound & secreted forms of antibodies and regulation of expression of immunoglobulin genes have also been discussed.Moreover, you will also get to know what is passive immunity and what is active immunity.We will also discuss the differences between polyclonal and monoclonal antibodies. In this course, the hybridoma technology has been discussed in detail and how it can be used to mass produce monoclonal antibodies? And how monoclonal antibodies can be used as therapeutics?Additionally this course will introduce you to various engineered therapeutic antibodies like chimeric monoclonal antibodies, humanised monoclonal antibodies and fully human monoclonal antibodies. In this course, you will get to know how the antibody structure can be leveraged to create immunotoxins, bispecific antibodies, abzymes etc for the treatment of cancer, arthritis, other viral, hormonal and autoimmune diseases.In this course we will discuss what is convalescent plasma therapy or passive antibody therapy and how it is being used for the treatment of COVID-19 disease, the current ongoing pandemic. Last but not the least, the course will also highlight the relevance of antibodies in therapeutics and diagnostics.With a 30 day return policy, there is nothing to lose. If you feel the course is not worth your money, you can return it and get your money back. Though, we assure you that you will not be disappointed by your wise decision of enrolling in this course.Who this course is for:The course is designed for medical students, doctors, researchers and students of biology, immunology, biotechnology, genetics, molecular biology, cell biology and bioinformatics disciplinesAny student who has immune system as a subject in their curriculumAnyone looking to study biology or immunology at college or university and wants quick, to the point knowledge about antibodiesNewly qualified teachers who need some great resources on antibodiesAnyone who wants to get an in-depth knowledge about antibodies and our immune system
Overview
| torrent name | size | uploader | age | seed | leech |
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Udemy - Peptides - Cosmetics, Biology, Microbiology and Biotechnology Posted by
freecoursewb in Other
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376.2 MB | freecoursewb | 2 months | 7 | 3 |
| 655.7 MB | freecoursewb | 4 months | 10 | 9 | |
| 714.3 MB | freecoursewb | 8 months | 0 | 0 | |
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